Tesamorelin

GHRH analog · lyophilized vial

$99per 10 mg vial · USD

Tesamorelin is a synthetic 44-amino-acid analog of growth-hormone-releasing hormone — C221H366N72O67S, 5135.9 g/mol — stabilised by a trans-3-hexenoic acid group at the N-terminus that protects it from enzymatic cleavage. It is the most clinically documented GHRH analog, studied for growth-hormone secretion and visceral adipose tissue in HIV-associated lipodystrophy. APX Labs supplies it as a 10 mg lyophilized vial, ≥99% purity by HPLC/MS, with a batch-specific COA. Research use only.

Key facts

Class: GHRH(1-44) analog, N-terminal trans-3-hexenoic acid modification
Formula: C221H366N72O67S · 5135.9 g/mol
Research contexts in the literature: GH secretion, visceral adipose tissue and liver enzymes in HIV lipodystrophy, muscle-fat composition
Format: 10 mg lyophilized vial — reconstitute with bacteriostatic water
Documentation: independent HPLC/MS test, batch-specific COA in every order

✦ COA included✦ Cold-chain shipping✦ Discreet packaging

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Specifications

Research category: Growth & Performance
Formula / short form: C221H366N72O67S
Molecular weight: 5135.9 g/mol
Quantity per vial: 10 mg
Purity: ≥99% (HPLC/MS, per-lot COA)
Test method: HPLC / MS
Form: Lyophilized powder
Documentation: Batch-specific COA ships with every order

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What is tesamorelin?

Tesamorelin is native human GHRH(1-44) with a single N-terminal modification that makes it resistant to the enzyme DPP-IV. Unlike most compounds in this catalog it has an extensive clinical literature, because a pharmaceutical formulation was developed for a specific HIV-related indication. The research-grade material APX Labs supplies is the same peptide sequence, tested to research-reagent standards, and is sold strictly for laboratory use.

What is tesamorelin studied for in research?

Visceral adipose tissue and liver markers. Multiple studies in people with HIV report reductions in visceral fat with associated changes in liver enzymes [1] and fat quality [2].
Muscle composition. A 2019 study examined muscle fat and muscle area [3].
Use alongside other therapy. A 2024 paper examined tesamorelin in people with HIV on integrase inhibitors [4].

These are clinical research findings in a specific patient population under medical supervision. They are not claims about the research-grade material sold here, which is not a drug and is not for human use.

Tesamorelin vs CJC-1295

Both are stabilised GHRH analogs. Tesamorelin is the full 44-residue sequence with an N-terminal cap; CJC-1295 is a 29-residue fragment with four amino-acid substitutions. See GHRH analogs explained for the side-by-side.

Specifications, purity and documentation

Identity by mass spectrometry (expected ~5,135.9 g/mol), purity by HPLC, batch-specific COA in every order. How to read the COA →

Tesamorelin — frequently asked

What is tesamorelin?⌄

Tesamorelin is a synthetic 44-amino-acid GHRH analog with an N-terminal modification for enzyme stability. It is studied for growth-hormone secretion and visceral adipose tissue, chiefly in HIV-associated lipodystrophy research. The research-grade material sold here is for laboratory use only.

Is research-grade tesamorelin the same as the prescription product?⌄

It is the same peptide sequence, but it is not a drug product: it is not manufactured, labelled, or approved for human use, and is sold strictly as a laboratory research reagent.

How should tesamorelin be stored?⌄

Store the lyophilized vial cold and away from light; after reconstitution with bacteriostatic water, refrigerate and use within the window on the COA.

References

Published research cited for context only. Citing a study does not imply APX Labs product was used in it, and is not a claim of any effect.

Stanley TL, et al. (2017). Visceral fat reduction with tesamorelin is associated with improved liver enzymes in HIV. AIDS. PubMed ↗
Fourman LT, et al. (2021). Tesamorelin improves fat quality independent of changes in fat quantity. AIDS. PubMed ↗
Adrian S, et al. (2019). The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area. J Frailty Aging. PubMed ↗
Lake JE, et al. (2024). Efficacy and safety of tesamorelin in people with HIV on integrase inhibitors. AIDS. PubMed ↗

[ Research context ]

What is Tesamorelin studied for?

Investigated in metabolic research models for its studied effect on growth-hormone secretion and lipid regulation.

[ Handling ]

Reconstitution & storage

Ships lyophilized in a sealed vial. Store cold and away from light. Reconstitute with bacteriostatic water (not included); once reconstituted, keep refrigerated and use within the window documented on the COA.

[ Compliance ]

Research use only

Sold strictly for laboratory and research purposes. Not for human or veterinary use, and not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Read the policy → · What RUO means →