Selank

What is Selank?

Tuftsin is a naturally occurring tetrapeptide fragment of immunoglobulin G with immune-signalling activity. Selank extends it with Pro-Gly-Pro — the same stabilising tail used in Semax — producing a heptapeptide that has been studied since the 1990s by the Institute of Molecular Genetics in Moscow for behavioural rather than immune endpoints.

What is Selank studied for in research?

• Anxiolytic-type activity. A 2018 review in *Protein & Peptide Letters* collects the molecular work on Selank's studied anxiolytic activity [1].
• Adaptive behaviour under stress. Early work characterised Selank and related tuftsin-family peptides in stress-adaptation models [2].
• Withdrawal models. A 2014 rat study examined the compound in a modelled alcohol-withdrawal setting [3].

Rodent findings only — not claims of human effect.

Selank vs Semax

The two Russian-origin heptapeptides share a stabilising tail but nothing else: Selank derives from tuftsin and is studied for anxiolytic-type endpoints; Semax from ACTH(4-10) and is studied for neurotrophin expression. Full comparison: Semax vs Selank.

Specifications, purity and documentation

Identity by mass spectrometry (expected 751.9 g/mol), purity by HPLC, batch-specific COA in every order. How to read the COA →

Selank — frequently asked

Further reading

• How to Reconstitute Lyophilized Peptides for Laboratory Use — Lyophilized peptides arrive as a dry cake in a sealed vial. Turning that into a solution of known concentration is simple, but the details protect the material.
• Semax vs Selank: Two Russian Heptapeptides, Two Different Research Questions — They share a country of origin, a length and a stabilising tail — and almost nothing else. Here is how the research literature separates them.